| 產(chǎn)品編號(hào) | bs-0368R-BF594 |
| 英文名稱 | Rabbit Anti-Mouse IgM antibody |
| 中文名稱 | BF594標(biāo)記的兔抗小鼠IgM |
| 別 名 | Mouse Immunoglobulin M |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse |
| 產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 免 疫 原 | Native Mouse IgM: full length |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 保存條件 | Store at -20℃ stable for 2 years (lyophilized powder). Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. |
