產(chǎn)品編號(hào) | IHC0272M |
英文名稱 | Mouse Calreticulin Ready-To-Use IHC Kit |
中文名稱 | 小鼠鈣網(wǎng)蛋白即用型免疫組化試劑盒 |
別 名 | CALR; Calregulin; cC1qR; CRP55; CRT; CRTC; ERp60; HACBP; HEL-S-99n; I79_008346; RO; SSA; Autoantigen RO; CALR protein; CALR_HUMAN; Endoplasmic reticulum resident protein 60; grp60; Sicca syndrome antigen A |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis. |
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