| 產(chǎn)品編號(hào) | IHC0268R |
| 英文名稱(chēng) | Rat Caspase-3 Ready-To-Use IHC Kit |
| 中文名稱(chēng) | 大鼠活化半胱胺酸蛋白酶蛋白-3即用型免疫組化試劑盒 |
| 別 名 | A830040C14Rik; AC-3; Apopain; CASP-3; CASP3; Caspase-3; CC3; CPP-32; CPP32; CPP32B; Lice; mldy; SCA-1; Yama; Apopain; CASP 3; Caspase 3; Caspase3; CPP 32; Cysteine protease CPP32; Protein Yama; SCA 1; SREBP cleavage activity 1 |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded rat spleen tissue slide using IHC0268R (Rat Caspase-3 IHC Kit).
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