| 產(chǎn)品編號(hào) | IHC0264R |
| 英文名稱 | Rat P Glycoprotein Ready-To-Use IHC Kit |
| 中文名稱 | 大鼠P-糖蛋白即用型免疫組化試劑盒 |
| 別 名 | ABC20; ABCB1; Abcb1a; Abcb1b; Abcb4; CD243; CLCS; Evi32; GP170; mdr; mdr-3; MDR1; Mdr1a; Mdr1b; Mdr3; P-GP; Pgp; PGP1; PGP2; Pgy-1; Pgy-3; PGY1; Pgy1-1; PGY2; Pgy3; ATP binding cassette; sub family B (MDR/TAP); member 1; ATP-binding cassette sub-family B member 1; Colchicin sensitivity; Doxorubicin resistance; MDR1_HUMAN; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; P-glycoprotein 1 |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded rat brain tissue slide using IHC0264R (Rat P Glycoprotein IHC Kit).
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