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P Glycoprotein Ready-To-Use IHC Kit (IHC0264)  
~~~促銷,代碼IHC202409~~~
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產(chǎn)品編號 IHC0264
英文名稱 P Glycoprotein Ready-To-Use IHC Kit
中文名稱 P-糖蛋白即用型免疫組化試劑盒
別    名 ABC20; ABCB1; Abcb1a; Abcb1b; Abcb4; CD243; CLCS; Evi32; GP170; mdr; mdr-3; MDR1; Mdr1a; Mdr1b; Mdr3; P-GP; Pgp; PGP1; PGP2; Pgy-1; Pgy-3; PGY1; Pgy1-1; PGY2; Pgy3; ATP binding cassette; sub family B (MDR/TAP); member 1; ATP-binding cassette sub-family B member 1; Colchicin sensitivity; Doxorubicin resistance; MDR1_HUMAN; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; P-glycoprotein 1  
保存條件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
產(chǎn)品介紹 The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

產(chǎn)品圖片
Immunohistochemical analysis of paraffin embedded mouse liver tissue slide using IHC0264 (P Glycoprotein IHC Kit).
Immunohistochemical analysis of paraffin embedded human liver tissue slide using IHC0264 (P Glycoprotein IHC Kit).
Immunohistochemical analysis of paraffin embedded rat liver tissue slide using IHC0264 (P Glycoprotein IHC Kit).
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