| 產(chǎn)品編號(hào) | IHC0252R |
| 英文名稱 | Rat GADD153 Ready-To-Use IHC Kit |
| 中文名稱 | 大鼠GADD153即用型免疫組化試劑盒 |
| 別 名 | CEBPZ; CHOP; CHOP-10; CHOP10; DDIT3; GADD153; C/EBPzeta; DDIT3 / CHOP |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane. |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded rat brain tissue slide using IHC0252R (Rat GADD153 IHC Kit).
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