| 產(chǎn)品編號 | IHC0252 |
| 英文名稱 | GADD153 Ready-To-Use IHC Kit |
| 中文名稱 | GADD153即用型免疫組化試劑盒 |
| 別 名 | CEBPZ; CHOP; CHOP-10; CHOP10; DDIT3; GADD153; C/EBPzeta; DDIT3 / CHOP |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane. |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded mouse brain tissue slide using IHC0252 (GADD153 IHC Kit).
Immunohistochemical analysis of paraffin embedded human skeletal muscle tissue slide using IHC0252 (GADD153 IHC Kit).
Immunohistochemical analysis of paraffin embedded rat kidney tissue slide using IHC0252 (GADD153 IHC Kit).
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