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Human CK18 Ready-To-Use IHC Kit (IHC0249H)  
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產(chǎn)品編號(hào) IHC0249H
英文名稱 Human CK18 Ready-To-Use IHC Kit
中文名稱 人細(xì)胞角蛋白18即用型免疫組化試劑盒
別    名 CK-18; CK18; CYK18; K18; Kerd; Krt1-18; KRT18; PIG46  
克 隆 號(hào)
適用樣品基質(zhì) FFPE tissue
保存條件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Cytokeratin 18 (Keratin 18, KRT18, type I cytoskeletal 18) belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18. Further, cytokeratin 18 is found primarily in non-squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas, but not in squamous cell carcinomas. Hepatocellular carcinomas express only cytokeratins 8 and 18. Mutations in the cytokeratin 18 gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for the cytokeratin 18 gene. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

SWISS:
P05783

Gene ID:
3875

產(chǎn)品圖片
Immunohistochemical analysis of paraffin embedded human endometrium tissue slide using IHC0249H (Human CK18 IHC Kit).
Immunohistochemical analysis of paraffin embedded human pancreatic cancer tissue slide using IHC0249H (Human CK18 IHC Kit).
Immunohistochemical analysis of paraffin embedded human gastric cancer tissue slide using IHC0249H (Human CK18 IHC Kit).
Immunohistochemical analysis of paraffin embedded human renal carcinoma tissue slide using IHC0249H (Human CK18 IHC Kit).
Immunohistochemical analysis of paraffin embedded human kidney tissue slide using IHC0249H (Human CK18 IHC Kit).
Immunohistochemical analysis of paraffin embedded human breast cancer tissue slide using IHC0249H (Human CK18 IHC Kit).
Immunohistochemical analysis of paraffin embedded human mammary gland tissue slide using IHC0249H (Human CK18 IHC Kit).
Immunohistochemical analysis of paraffin embedded human brain tissue slide using IHC0249H (Human CK18 IHC Kit).
Immunohistochemical analysis of paraffin embedded human colon cancer tissue slide using IHC0249H (Human CK18 IHC Kit).
Immunohistochemical analysis of paraffin embedded human liver tissue slide using IHC0249H (Human CK18 IHC Kit).
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